For a woman with profound brain damage, SM seems rather unremarkable. Her IQ tests normal; she speaks like an average person, and her memory and perception show no sign of dysfunction. But the 44-year-old woman does have one very specific, very unusual, and for neuroscientists, a very interesting impairment: she has no amygdala, the part of the brain that’s the central switching box for analyzing external threats. SM has no fear.
SM’s story received a great deal of attention lately thanks to a paper describing her condition that was published in the journal Current Biology. (Neurophilosopy did a particularly incisive and digestible rundown of the paper’s findings.) The authors introduced SM, whose amygdalae were destroyed by a genetic condition called Urbach-Wiethe disease, to a variety of situations that a normal person might well find fear-inducing. They took her to an exotic animal shop where she handled snakes and looked at tarantulas; they took her to a “haunted house” attraction; showed her clips of movies like “The Blair Witch Project”; and told her that Sarah Palin had been appointed to the Supreme Court. (OK, not the last one). In each case, she showed no signs of fear, and reported feeling no anxiety. In fact, while scampering through the haunted house she was so delighted and curious that she scared one of the “monsters” by trying to poke its mask.
For most of us, fear seems like a negative emotion, one that stresses us out and inhibits us from trying things that might make our life more rewarding. But as the Current Biology paper makes clear, SM’s fearlessness has cost her a great deal. On the most obvious level, it has left her vulnerable to all kinds of dangers. She lives in a dangerous part of a big city, and several times she has walked obliviously into potentially violent encounters. One time, she was held up at gunpoint; another time, a drug addict accosted her and held a knife to her throat. Intriguingly, though she did not feel scared during those encounters, she did report feeling angry and upset afterward. Her emotional deficit is quite specific.
But in a sense SM’s fearlessness is not the worst part of losing her amygdalae. Continue reading The Strange Lives of Women With No Fear